database
DNA databases
Entrez is the gateway to six major searchable databases of; nucleotides, proteins, 3-D structures, genomes, taxonomy and literature (PubMed). The Genomes database includes the complete genomes of 15 organisms, and chromosome maps of Drosophila, C. elegans, mouse and all human chromosomes. Searching is simple and detailed help is available
The Genome Database contains all of the genomic mapping data from the Human Genome Project. Includes descriptions of regions of the genome (genes, clones, fragile sites etc.), maps of the human genome, and mutations and polymorphisms.
GenBank , the NIH genetic sequence database, provides an annotated, fully searchable collection of all publicly available DNA sequences. GenBank coordinates all sequence information on a daily basis with the DNA DataBank of Japan (DDBJ), and the European Molecular Biology Laboratory (EMBL). You may search Genbank via Entrez
or BLAST. You may also submit sequence datato GenBank via the WWW.
BLAST searches all available sequence databases for sequence similarity (homology, identity) with both nucleotide and protein sequences. By searching for local alignments, BLAST can detect similarity in isolated regions of a sequence. There are a number of programs, but to start just paste your sequence into the basic BLAST box and hit submit. Good FAQs available.
Online Mendelian Inheritance in Man database. A catalog of human genes and genetic disorders, and includes information about specific genes that is extensively referenced, images of clinical phenotypes, and other relevant database links. An excellent place to begin to learn about a specific disease gene of interest.