Example topic (first) sentences for each part of an introduction:
(1. Background)
Parkinson’s disease results from a relentless progressive loss of dopamine neurons in the midbrain. …
(2. More specific)
Considerable evidence suggests that neurotrophic factors which promote the survival or differentiation of developing neurons may also protect mature neurons in vivo. …
(2. More specific)
Less is known about the ability of trophic factors to protect midbrain dopamine neurons. …
(3. Aims)
The present study was designed to investigate a possible neuroprotective role for GDNF in rats that receive specific injury to midbrain dopamine neurons by 6-OHDA treatment. …
(4. Concluding)
Our results demonstrate a significant neuroprotective effect of GDNF pretreatment.
