- Behavioral Economic Laboratory Research in Tobacco Regulatory Science., Equipments, Exosomes, Gels, Isotypes, Laboratory Medicine, PCR, Pcr Kits, Peptides, Portable Motion-Analysis Device for Upper-Limb Research, Ria Kits, RNA, Test Kits
Robust Data Integration Method for Classification of Biomedical Data
Robust Data Integration Method for Classification of Biomedical Data We present a protocol for integrating two types of biological data – clinical and molecular – for more effective classification of patients with cancer. The proposed approach is a hybrid between early and late data integration strategy. In this hybrid protocol, the set of informative clinical features is extended by the classification results based on molecular data sets. The results are then treated as new synthetic variables. The hybrid protocol was applied to METABRIC breast cancer samples and TCGA urothelial bladder carcinoma samples. Various data types were used for clinical endpoint prediction: clinical data, gene expression, somatic copy number aberrations, RNA-Seq, methylation, and…